Gene analysis of heterozygous protein C deficiency in a patient with pulmonary arterial thromboembolism.

doi:10.1164/ajrccm/145.6.1491

Back to search

Article

Gene analysis of heterozygous protein C deficiency in a patient with pulmonary arterial thromboembolism.

The American review of respiratory disease - 1 Jun 1992

Ohwada A, Takahashi H, Uchida K, Nukiwa T, Kira S

Abstract excerpt

A 16-yr-old male patient with heterozygous protein C deficiency developed acute pulmonary thromboembolism. The patient had low levels of plasma protein C antigen and activity (33 and 35% of normal, respectively). Analysis of the protein C gene by polymerase chain reaction (PCR) and direct sequenc...

Topics

Adolescent
Heterozygote
Humans
Male
Mutation
Pedigree
Polymerase Chain Reaction
Protein C
Protein C Deficiency
Pulmonary Embolism
RNA, Messenger

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.