Article
From multipotent stem cell to adipocyte
15 Jun 2005
Abstract excerpt
The increase of adipose tissue mass that accompanies obesity is due both to an increase in adipocyte number (hyperplasia) and size (hypertrophy) (Shepherd et al., 1993) (Fig. 1). Hyperplasia results from the recruitment of preadipose cells from a population of pluripotent stem cells that reside in the vascular stroma of adipose tissue. These stem cells have the capacity to undergo commitment to adipose, muscle,...
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