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<i>In vivo</i> formation and repair of DNA double-strand breaks after computed tomography examinations

13 Jun 2005

Abstract excerpt

Ionizing radiation can lead to a variety of deleterious effects in humans, most importantly to the induction of cancer. DNA double-strand breaks (DSBs) are among the most significant genetic lesions introduced by ionizing radiation that can initiate carcinogenesis. We have enumerated gamma-H2AX foci as a measure for DSBs in lymphocytes from individuals undergoing computed tomography examination of the thorax...

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PMID: 15956203
DOI: 10.1073/pnas.0501895102

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