Genetics of type 2 diabetes: an overview for the millennium.

doi:10.1089/15209150050194260

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Article

Genetics of type 2 diabetes: an overview for the millennium.

Diabetes technology & therapeutics - 1 Jan 2000

Elbein S C

Abstract excerpt

Abundant evidence supports a genetic predisposition to both type 2 diabetes and the traits that precede diabetes (insulin resistance and insulin secretion). Unusual causes of diabetes have been identified, including autosomal dominant, single gene forms due to mutations of glucokinase, the hepatocyte nuclear factors, and insulin promoter factor 1. Mitochondrial mutations also may cause type 2 diabetes, but...

Topics

Animals
Diabetes Mellitus, Type 2
Disease Models, Animal
Genetic Linkage
Genetic Predisposition to Disease
Genome, Human
Humans
Insulin
Insulin Resistance
Insulin Secretion
Prediabetic State

Source

Open in PubMed

Identifiers

PMID: 11467342
DOI: 10.1089/15209150050194260

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