Article
A silanized hydroxypropyl methylcellulose hydrogel for the three-dimensional culture of chondrocytes.
Biomaterials - 1 Nov 2005
Vinatier C, Magne D, Weiss P, Trojani C, Rochet N, Carle G F, Vignes-Colombeix C, Chadjichristos C, Galera P, Daculsi G, Guicheux J
Abstract excerpt
Articular cartilage has limited intrinsic repair capacity. In order to promote cartilage repair, the amplification and transfer of autologous chondrocytes using three-dimensional scaffolds have been proposed. We have developed an injectable and self-setting hydrogel consisting of hydroxypropyl methylcellulose grafted with silanol groups (Si-HPMC). The aim of the present work is to assess both the in vitro...
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