Article
Microcolony formation: a novel biofilm model of Pseudomonas aeruginosa for the cystic fibrosis lung.
Journal of medical microbiology - 1 Jul 2005
Sriramulu Dinesh D, Lünsdorf Heinrich, Lam Joseph S, Römling Ute
Abstract excerpt
Pseudomonas aeruginosa colonizing the lung of cystic fibrosis patients is responsible for a decline in health and poor prognosis for these patients. Once established, growth of P. aeruginosa in microcolonies makes it very difficult to eradicate the organisms by antimicrobial treatment. An artificial sputum medium was developed to mimic growth of P. aeruginosa in the cystic fibrosis lung habitat and it was found...
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