Article
Effect of apolipoprotein E (apoE) phenotype on the apoE content of CSF-HDL in children.
Clinica chimica acta; international journal of clinical chemistry - 1 Jun 2005
Hirayama Satoshi, Miida Takashi, Obayashi Konen, Yamazaki Fusako, Yamazaki-Sakurai Miho, Ito Masayuki, Saito Yuji, Hanyu Osamu, Suzuki Katsunori, Aizawa Yoshifusa
Abstract excerpt
BACKGROUND: The majority of the lipoprotein in cerebrospinal fluid (CSF) is apolipoprotein E (apoE)-containing HDL. Since neuronal cells express lipoprotein receptors which recognize apoE, apoE in CSF-HDL is believed to be important for the development of central nervous system (CNS) in children. In adults, the apoE phenotype affects the plasma apoE concentration and the epsilon 4 allele is a risk factor for...
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