Article
Locus-specific brackets for reliable typing of Y-chromosome short tandem repeat markers.
Electrophoresis - 1 Jun 2005
Butler John M, Appleby Jill E, Duewer David L
Abstract excerpt
Short tandem repeat (STR) loci, widely used as genetic markers in disease diagnostic studies and human identity applications, are traditionally genotyped through comparison of allele sizes to a sequenced allelic ladder. Allelic ladders permit a floating bin allele calling method to be utilized, which enables reliable allele calling across laboratories, instrument platforms, and electrophoretic conditions. Precise...
Topics
- Alleles
- Chromosomes, Human, Y
- Electrophoresis, Capillary
- Genetic Techniques
- Humans
- Male
- Microsatellite Repeats
- Polymerase Chain Reaction
