Article
Cytokine gene polymorphism in Iranian patients with chronic myelogenous leukaemia.
International journal of immunogenetics - 1 Jun 2005
Amirzargar A A, Bagheri M, Ghavamzadeh A, Alimoghadam K, Khosravi F, Rezaei N, Moheydin M, Ansaripour B, Moradi B, Nikbin B
Abstract excerpt
Chronic myelogenous leukaemia (CML) is a disorder of the haematopoietic stem cell that results in malignant expansion of myeloid cells with a cytogenetic abnormality, and translocation between chromosomes 9 and 22, known as the Philadelphia chromosome. It has been hypothesized that genetic factors other than histocompatibility disparity may play a role in predisposition to developing CML. In this regard, T helper...
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