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Article

A kissing-loop interaction in a hammerhead viroid RNA critical for its in vitro folding and in vivo viability.

RNA (New York, N.Y.) - 1 Jul 2005

Gago Selma, De la Peña Marcos, Flores Ricardo

Abstract excerpt

Chrysanthemum chlorotic mottle viroid (CChMVd) RNA (398-401 nucleotides) can form hammerhead ribozymes that play a functional role in its replication through a rolling-circle mechanism. In contrast to most other viroids, which adopt rod-like or quasi-rod-like secondary structures of minimal free energy, the computer-predicted conformations of CChMVd and Peach latent mosaic viroid (PLMVd) RNAs are branched....

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Identifiers

PMID: 15928342
DOI: 10.1261/rna.2230605
PMCID: PMC1370792

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