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Article

Gene expression and phenotypic characterization of mouse heart after chronic constant or intermittent hypoxia.

Physiological genomics - 11 Aug 2005

Fan Chenhao, Iacobas Dumitru A, Zhou Dan, Chen Qiaofang, Lai James K, Gavrialov Orit, Haddad Gabriel G

Abstract excerpt

Chronic constant hypoxia (CCH), such as in pulmonary diseases or high altitude, and chronic intermittent hypoxia (CIH), such as in sleep apnea, can lead to major changes in the heart. Molecular mechanisms underlying these cardiac alterations are not well understood. We hypothesized that changes in gene expression could help to delineate such mechanisms. The current study used a neonatal mouse model in CCH or CIH...

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Identifiers

PMID: 15928208
DOI: 10.1152/physiolgenomics.00217.2004
PMCID: PMC2856928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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