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Article

Increased cardiovascular morbidity and mortality in type 2 diabetes is associated with the glutathione S transferase theta-null genotype: a Go-DARTS study.

Circulation - 7 Jun 2005

Doney Alex S F, Lee Simon, Leese Graham P, Morris Andrew D, Palmer Colin N A

Abstract excerpt

BACKGROUND: Glutathione S-transferases (GSTs) modulate oxidative stress, and variation in GST genes has been associated with cardiovascular disease risk. We prospectively determined smoking-related cardiovascular morbidity by GST genotype in a large cohort of individuals with type 2 diabetes using a population-based diabetes research database (DARTS). METHODS AND RESULTS: We performed a cohort study of 2015...

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Source

Identifiers

PMID: 15927971
DOI: 10.1161/CIRCULATIONAHA.104.509224

Genes

GSTT1
GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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