Article
Cytokine gene polymorphisms in gastric cancer patients from two Italian areas at high and low cancer prevalence.
Cytokine - 7 Jun 2005
Perri F, Piepoli A, Bonvicini C, Gentile A, Quitadamo M, Di Candia M, Cotugno R, Cattaneo F, Zagari M R, Ricciardiello L, Gennarelli M, Bazzoli F, Ranzani G N, Andriulli A
Abstract excerpt
Polymorphisms of interleukin-1beta (IL-1beta), IL-1 receptor antagonist (IL1-RN), and tumor necrosis factor-alpha (TNF-alpha) genes are supposed to be key determinants of gastric cancer risk. Our aim was to study the association between these polymorphisms and gastric cancer in two areas characterized by high (Pavia/Bologna, North Italy) and low (San Giovanni Rotondo, South Italy) gastric cancer prevalence....
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