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Article

C/EBPα Regulates Human Adiponectin Gene Transcription Through an Intronic Enhancer

1 Jun 2005

Abstract excerpt

Adiponectin is an adipose-derived hormone that enhances insulin sensitivity and plays an important role in regulating energy homeostasis. Here, we demonstrate that the DNA encoding the first intron of the human adiponectin gene contains an intronic enhancer that regulates adiponectin gene expression in an adipose tissue-specific manner. Insertion of the DNA encoding the first intron into reporter constructs...

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Identifiers

PMID: 15919796
DOI: 10.2337/diabetes.54.6.1744

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