Article
[How bacteria resist antibiotics: a primary form of collective intelligence?].
Bulletin de l'Academie nationale de medecine - 1 Jan 2004
Pechère Jean-Claude
Abstract excerpt
Bacteria produce inhibitory enzymes (beta-lactamases, etc), block antibiotic attachment to target molecules (MRSA, etc.), extrude antibiotics from the cell by active efflux systems (multidrug resistant pseudomonas, etc) or limit antibiotic penetration through the outer membrane in Gram negatives. Genetically, resistance occurs after mutation or horizontal transfers (transformation, transduction, conjugation) of...
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