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Article

BRCA1 and BRCA2 as ovarian cancer susceptibility genes.

Carcinogenesis - 1 Oct 2005

Sowter Heidi M, Ashworth Alan

Abstract excerpt

Individuals carrying germline mutations in one allele of the BRCA1 or BRCA2 genes are at significantly increased risk of developing cancer. Although the increased risk of breast cancer is often highlighted, cancer at several other sites is also considerably more common in these individuals. Here, we discuss existing knowledge of the role of BRCA1 and BRCA2 mutation in pre-disposition to ovarian cancer. The risk...

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Source

Identifiers

PMID: 15917310
DOI: 10.1093/carcin/bgi136

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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