Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Linkage exclusion analysis of two candidate regions on chromosomes 7 and 11: leptin and UCP2/UCP3 are not QTLs for obesity in US Caucasians.

Biochemical and biophysical research communications - 1 Jul 2005

Guo Jing-Jing, Liu Yong-Jun, Li Miao-Xing, Yang Yan-Jun, Recker Robert R, Deng Hong-Wen

Abstract excerpt

Leptin (LEP) and the uncoupling proteins 2 and 3 (UCP2/UCP3) are key molecules involved in the regulation of food intake and energy expenditure. However, their contribution to variation of obesity phenotypes in the general population remains controversial. The present study is to investigate whether chromosomal regions 7q and 11q, which contain LEP and UCP2/UCP3, respectively, can be excluded for linkage with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 11
Share to Chromosomes, Human, Pair 7

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ion Channels

Share to Leptin

Share to Membrane Transport Proteins

Share to Mitochondrial Proteins

Share to Uncoupling Protein 2

Share to Uncoupling Protein 3

Source

Identifiers

PMID: 15910756
DOI: 10.1016/j.bbrc.2005.04.160

Genes

UCP2
UCP3
LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Linkage exclusion analysis of two candidate regions on chromosomes 7 and 11: leptin and UCP2/UCP3 are not QTLs for obesity in US Caucasians.PMID 15910756Read ↗

Linkage exclusion analysis of the chromosome 11 region containing UCP2 and UCP3 with obesity-related phenotypes in Mexican Americans.Semantic proximity Read ↗

Further evidence for a QTL influencing body mass index on chromosome 7p from a genome-wide scan in Dutch families.Semantic proximity Read ↗

Linkage and association analyses of the UCP3 gene with obesity phenotypes in Caucasian families.Semantic proximity Read ↗

LOD score exclusion analyses for candidate QTLs using random population samples.Semantic proximity Read ↗

An autosomal genomic scan for loci linked to plasma leptin concentration in Pima Indians.Semantic proximity Read ↗

Tests of linkage and/or association of the LEPR gene polymorphisms with obesity phenotypes in Caucasian nuclear families.Semantic proximity Read ↗

Linkage exclusion mapping with bone size in 79 Caucasian pedigrees.Semantic proximity Read ↗

LOD score exclusion analyses for candidate genes using random population samples.Semantic proximity Read ↗

Exclusion of linkage of Crohn's disease to previously reported regions on chromosomes 12, 7, and 3 in the Belgian population indicates genetic heterogeneity.Semantic proximity Read ↗

Linkage exclusion analysis of two important chromosomal regions for height.Semantic proximity Read ↗

No linkage to obesity in candidate regions of chromosome 2 and 10 in a selected sample of Swedish twins.Semantic proximity Read ↗

Genetic markers at the leptin (OB) locus are not significantly linked to hypertension in African Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.