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Article

Reduced endothelial secretion and plasma levels of transforming growth factor-beta1 in patients with hereditary hemorrhagic telangiectasia type 1.

Cardiovascular research - 1 Oct 2005

Letarte Michelle, McDonald Merry-Lynn, Li Chenggang, Kathirkamathamby Kirishanthy, Vera Sonia, Pece-Barbara Nadia, Kumar Shant

Abstract excerpt

OBJECTIVE: To determine if patients with hereditary hemorrhagic telangiectasia (HHT) show alterations in transforming growth factor (TGF)-beta and its pathways. METHODS: Blood samples were obtained from HHT patients and controls, while endothelial cells were derived from umbilical veins of newborns (HUVEC) from HHT families. TGF-beta1 in plasma, or secreted by HUVEC, and plasma endoglin levels were measured by...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Telangiectasia, Hereditary Hemorrhagic

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Share to Vascular Cell Adhesion Molecule-1

Source

Identifiers

PMID: 15907823
DOI: 10.1016/j.cardiores.2005.04.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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