Intrinsic Resistance of Hepatocytes to Complement-Mediated Injury

Abstract excerpt

When activated on or in the vicinity of cells, complement usually causes loss of function and sometimes cell death. Yet the liver, which produces large amounts of complement proteins, clears activators of complement and activated complexes from portal blood without obvious injury or impaired function. We asked whether and to what extent hepatocytes resist injury and loss of function mediated by exposure to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Liver Disease Diagnosis and Treatment
• Share to Liver physiology and pathology