Article
The crucial role of trehalose and structurally related oligosaccharides in the biosynthesis and transfer of mycolic acids in Corynebacterineae.
The Journal of biological chemistry - 15 Jul 2005
Tropis Marielle, Meniche Xavier, Wolf Andreas, Gebhardt Henrike, Strelkov Sergey, Chami Mohamed, Schomburg Dietmar, Krämer Reinhard, Morbach Susanne, Daffé Mamadou
Abstract excerpt
Trehalose (alpha-D-glucopyranosyl-alpha'-D-glucopyranoside) is essential for the growth of the human pathogen Mycobacterium tuberculosis but not for the viability of the phylogenetically related corynebacteria. To determine the role of trehalose in the physiology of these bacteria, the so-called Corynebacterineae, mutant strains of Corynebacterium glutamicum unable to synthesize trehalose due to the knock-out of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
