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Article

Novelty seeking: interaction between parental alcohol use and dopamine D4 receptor gene exon III polymorphism over 17 years.

Psychiatric genetics - 1 Jun 2005

Lahti Jari, Räikkönen Katri, Ekelund Jesper, Peltonen Leena, Raitakari Olli T, Keltikangas-Järvinen Liisa

Abstract excerpt

Recent meta-analyses have questioned the association between the dopamine receptor D4 (DRD4) gene polymorphism and the temperament trait of novelty seeking, and proposed an interaction between the polymorphism and other factors. We wanted to test whether parental alcohol use during childhood moderated the effect of an offspring dopamine receptor gene (DRD4) polymorphism on the temperament trait of novelty seeking...

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Source

Identifiers

PMID: 15900228
DOI: 10.1097/00041444-200506000-00010

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novelty seeking: interaction between parental alcohol use and dopamine D4 receptor gene exon III polymorphism over 17 years.PMID 15900228Read ↗

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Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking.Semantic proximity Read ↗

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Additional evidence for an association between the dopamine D4 receptor (D4DR) exon III repeat polymorphism and the human personality trait of Novelty Seeking.Semantic proximity Read ↗

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