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Article

ERS1 encodes a functional homologue of the human lysosomal cystine transporter.

The FEBS journal - 1 May 2005

Gao Xiao-Dong, Wang Ji, Keppler-Ross Sabine, Dean Neta

Abstract excerpt

Cystinosis is a lysosomal storage disease caused by an accumulation of insoluble cystine in the lumen of the lysosome. CTNS encodes the lysosomal cystine transporter, mutations in which manifest as a range of disorders and are the most common cause of inherited renal Fanconi syndrome. Cystinosin, the CTNS product, is highly conserved among mammals. Here we show that the yeast Ers1 protein and cystinosin are...

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Share to Amino Acid Transport Systems, Neutral
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15885099
DOI: 10.1111/j.1742-4658.2005.04670.x

Genes

CTNS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ERS1 encodes a functional homologue of the human lysosomal cystine transporter.PMID 15885099Read ↗

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