Article
Genes contributing to risk for common forms of stroke.
Trends in molecular medicine - 1 May 2005
Gulcher Jeffrey R, Gretarsdottir Solveig, Helgadottir Anna, Stefansson Kari
Abstract excerpt
The quest for disease genes that confer risk for stroke is now being undertaken using three complementary approaches. Positional cloning using rare Mendelian phenocopies of stroke has found genes that contribute to rare forms of stroke but, so far, not to the common forms of stroke. Candidate-gene case-control association studies using the common forms of stroke have found suggestive associations of modest...
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