Article
Calcitonin gene polymorphism CALCA-624 (T/C) and ovarian cancer.
Environmental and molecular mutagenesis - 1 Jul 2005
Goodman Marc T, Ferrell Robert, McDuffie Katharine, Thompson Pamela J, Wilkens Lynne R, Bushley Abigail W, Tung Ko-Hui, Carney Michael E, Ness Roberta B
Abstract excerpt
In a previous analysis, we reported an inverse association of dietary calcium intake with the risk of ovarian cancer (Goodman et al. 2002. Am J Epidemiol 156:148-57). The CALCA gene codes for calcitonin, an important regulator of bone calcium metabolism. Data from a population-based case-control study conducted in Hawaii were used to examine the hypothesis that a T --> C transition 624 base pairs upstream (-624)...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Asian
- Calcitonin
- Calcitonin Gene-Related Peptide
- Calcium, Dietary
- Case-Control Studies
- DNA
- Female
- Genotype
- Hawaii
- Humans
