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Article

Variability and Laboratory Factors Affecting the Sperm Chromatin Structure Assay in Human Semen

2 May 2005

Abstract excerpt

During the past decade, the sperm chromatin structure assay (SCSA) has become an important tool for assessing semen quality in the human andrology laboratory. The SCSA uses the metachromatic properties of the fluorescent dye acridine orange (AO) in combination with flow cytometry to determine the sperm DNA susceptibility to denaturation in situ. The objective of this study was to evaluate laboratory factors...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15867004
DOI: 10.2164/jandrol.04056

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