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Increased expression of histone deacetylase 2 is found in human gastric cancer

1 Apr 2005

Abstract excerpt

Accumulated evidence has established that aberrant regulation of histone deacetylases (HDACs) is one of the major causes of the development of human malignancies. Among different iso-enzymes of HDAC and sirtuins grouped as the HDAC super family, little is known as to how histone deacetylase 2 (HDAC2) causes carcinogenesis in solid tumors. Here, in order to investigate the possible role of HDAC2 in gastric...

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PMID: 15865607
DOI: 10.1111/j.1600-0463.2005.apm_04.x

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