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Article

Genetic and environmental factors affecting the response to statin therapy in patients with molecularly defined familial hypercholesterolaemia.

Pharmacogenetics and genomics - 1 Apr 2005

Miltiadous George, Xenophontos Stavroulla, Bairaktari Eleni, Ganotakis Manolis, Cariolou Marios, Elisaf Moses

Abstract excerpt

Familial hypercholesterolaemia (FH) is the most common inherited metabolic disease characterized by elevated serum levels of low-density lipoprotein cholesterol (LDL-C) and ischaemic heart disease early in life. Early diagnosis and treatment are essential to prevent premature atherosclerosis in FH patients. The aim of our study was the evaluation of the effects of genetic [class of the LDL receptor (LDLR) gene...

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Share to Atorvastatin
Share to Cholesterol Ester Transfer Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heptanoic Acids

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Hyperlipoproteinemia Type II

Share to Lipoproteins, LDL

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Source

Identifiers

PMID: 15864114
DOI: 10.1097/01213011-200504000-00005

Genes

LDLR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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