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Article

Genetics of fibrosing lung diseases.

The European respiratory journal - 1 May 2005

Grutters J C, du Bois R M

Abstract excerpt

Genetic studies in familial lung fibrosis have demonstrated an association with surfactant protein C genes: two mutations have been found resulting in protein misfolding and causing type-II epithelial cell injury. Remarkably, different histological patterns were observed in the affected subjects, suggesting the influence of modifier genes and/or environmental factors. Surfactant protein C gene variations have...

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Share to Polymorphism, Genetic
Share to Pulmonary Fibrosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hermanski-Pudlak Syndrome

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Share to Pulmonary Surfactant-Associated Protein C

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Source

Identifiers

PMID: 15863652
DOI: 10.1183/09031936.05.00133404

Genes

TNF
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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