Article
The APOC3 SstI polymorphism is weakly associated with sporadic Alzheimer's disease in a Chinese population.
Neuroscience letters - 3 Jun 2005
Sun Yan, Shi Jiajun, Zhang Sizhong, Tang Mouni, Han Haiying, Guo Yangbo, Ma Cui, Liu Xiehe, Li Tao
Abstract excerpt
In order to clarify the relationship of apolipoprotein CIII (APOC3) polymorphism and sporadic Alzheimer's disease (AD) in Chinese, 165 sporadic AD patients and 174 age-matched elderly individuals were genotyped for the APOC3 SstI and apolipoprotein E (APOE) HhaI polymorphisms. As the result, the APOC3 3017G allele was found to be associated with AD in APOE epsilon4 allele noncarriers (chi2=4.433, P=0.035), and...
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