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Article

Survival motor neuron (SMN) protein: role in neurite outgrowth and neuromuscular maturation during neuronal differentiation and development

1 Jul 2002

Abstract excerpt

Childhood spinal muscular atrophy (SMA) is a common neuromuscular disorder caused by absent or deficient full-length survival motor neuron (SMN) protein. Clinical studies and animal models suggest that SMA is a developmental defect in neuromuscular interaction; however, the role of SMN in this process remains unclear. In the present study, we have determined the subcellular localization of SMN during...

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PMID: 12075005
DOI: 10.1093/hmg/11.14.1605

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Survival motor neuron (SMN) protein: role in neurite outgrowth and neuromuscular maturation during neuronal differentiation and developmentPMID 12075005Read ↗

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Survival motor neuron (SMN) protein in rat is expressed as different molecular forms and is developmentally regulatedSemantic proximity Read ↗

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