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Article

Retargeting mobile group II introns to repair mutant genes.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 May 2005

Jones John Patrick, Kierlin Monique N, Coon Robert G, Perutka Jiri, Lambowitz Alan M, Sullenger Bruce A

Abstract excerpt

Retroposable elements such as retroviral and lentiviral vectors have been employed for many gene therapy applications. Unfortunately, such gene transfer vectors integrate genes into many different DNA sequences and unintended integration of the vector near a growth-promoting gene can engender pat...

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Share to DNA Repair
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15851007
DOI: 10.1016/j.ymthe.2005.01.014

Genes

GLB1
HBB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15851007-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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