Choice of Gender in 5α-Reductase Deficiency: A Moving Target

Abstract excerpt

Steroid 5alpha-reductase deficiency is a rare, male-limited autosomal recessive disorder caused by mutation in the SRD5A2 gene resulting in a deficiency of dihydrotestosterone (DHT) during fetal development. Here we report an affected 46,XY adolescent who was born with incompletely virilized genitalia and was raised in the female gender. At 12 years of age, the patient requested feminizing genital surgery....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hormonal and reproductive studies
• Share to Sexual Differentiation and Disorders
• Share to Urologic and reproductive health conditions