Article
Selection of laboratory wild-type phenotype from natural isolates of Escherichia coli in chemostats.
Molecular biology and evolution - 1 May 1992
Mikkola R, Kurland C G
Abstract excerpt
We have followed, in glucose-limited chemostats, the evolution of natural isolates of Escherichia coli possessing maximal growth rates of 0.48-1.43 doublings/h. Under these conditions a rapid-growth phenotype similar to that of standard laboratory wild-type strains was selected so that after 280 generations all of the cultures were characterized by bacteria with maximum growth rates close to 1.33 doublings/h. The...
Topics
- Culture Media
- Escherichia coli
- Glucose
- Kinetics
- Phenotype
- Protein Biosynthesis
- Ribosomes
- Selection, Genetic