Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Thyrotrophin receptor antibody characteristics in a woman with long-standing Hashimoto's who developed Graves' disease and pretibial myxoedema.

Clinical endocrinology - 1 Sept 2012

Kamath C, Young S, Kabelis K, Sanders J, Adlan M A, Furmaniak J, Rees Smith B, Premawardhana L D

Abstract excerpt

CONTEXT: Sequential conversion of Hashimoto's thyroiditis (HT) to Graves' disease (GD) is uncommon. Distinct immune paradigms, paucity of functioning tissue in long-standing HT, and infrequent conversion of blocking (TBAb) to stimulating (TSAb) thyrotrophin receptor antibody (TRAb) may account for this. Molecular and crystal structure analysis helps delineate TSH receptor (TSHR)/TRAb interactions in detail. Such...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Blocking
Share to CHO Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cricetinae

Share to Cricetulus

Share to Graves Disease

Share to Hashimoto Disease

Share to Receptors, Thyrotropin

Share to Thyroxine

Source

Identifiers

PMID: 22891608
DOI: 10.1111/j.1365-2265.2012.04397.x

Genes

TSHR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Thyrotrophin receptor antibody characteristics in a woman with long-standing Hashimoto's who developed Graves' disease and pretibial myxoedema.PMID 22891608Read ↗

Thyrotropin receptor-associated diseases: from adenomata to Graves disease.Semantic proximity Read ↗

Relevance of TSH-receptor antibody levels in predicting disease course in Graves' orbitopathy: comparison of the third-generation TBII assay and Mc4-TSI bioassaySemantic proximity Read ↗

Immunological Drivers in Graves' Disease: NK Cells as a Master SwitcherSemantic proximity Read ↗

The phenotype of Graves' orbitopathy is associated with thyrotropin receptor antibody levels.Semantic proximity Read ↗

Immunopathogenesis of Graves’ ophthalmopathy: The role of the TSH receptorSemantic proximity Read ↗

Graves’ DiseaseSemantic proximity Read ↗

[Graves' disease].Semantic proximity Read ↗

Dichotomous responses to thyroid hormone treatment in a patient with primary hypothyroidism and thyroid hormone resistance.Semantic proximity Read ↗

Epitope heterogeneity of thyroid-stimulating antibodies predicts long-term outcome in Graves' patients treated with antithyroid drugs.Semantic proximity Read ↗

Stimulatory Thyrotropin Receptor Antibodies Are a Biomarker for Graves’ OrbitopathySemantic proximity Read ↗

Prolonged inappropriate TSH suppression during hypothyroidism after thyroid ablation in a patient with nonautoimmune familial hyperthyroidism.Semantic proximity Read ↗

A human monoclonal autoantibody to the thyrotropin receptor with thyroid-stimulating blocking activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.