Article
Monozygotic twins concordant for blood karyotype, but phenotypically discordant: a case of "mosaic chimerism".
American journal of medical genetics. Part A - 1 Jun 2005
Bourthoumieu Sylvie, Yardin Catherine, Terro Faraj, Gilbert Brigitte, Laroche Cécile, Saura Robert, Vincent Marie-Claire, Esclaire Françoise
Abstract excerpt
We report on 23 years old discordant monozygotic (MZ) twins, one with minor anomalies and mental delay, the other one being normal. Both had 46,XX,dup(11)(p12p15)/46,XX mosaicism in blood, with a similar proportion of abnormal cells (respectively, 16% and 17%). However, interphase fluorescence in situ hybridization (FISH) analysis performed on buccal smear and urinary sediment using specific probes located at the...
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