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Chimerism resulting from parthenogenetic activation and dispermic fertilization

20 Aug 2010

Abstract excerpt

Whole-body human chimerism is the result of two zygotes giving rise to one individual, and is a rarely detected condition. We have studied the molecular background and discuss the likely mechanism for the chimerism in a patient with a 46,XX/47,XY,+14 karyotype and ambiguous genitalia, cryptorchidism, pigment anomalies, and normal psychomotor development. We have used karyotyping, interphase-FISH and array-CGH...

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Share to Assisted Reproductive Technology and Twin Pregnancy
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PMID: 20803645
DOI: 10.1002/ajmg.a.33594

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