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Article

Understanding how combinations of HLA and KIR genes influence disease.

The Journal of experimental medicine - 4 Apr 2005

Rajagopalan Sumati, Long Eric O

Abstract excerpt

Combinations of HLA and killer cell immunoglobulin-like receptor (KIR) genes have been associated with diseases as diverse as autoimmunity, viral infections, reproductive failure, and now cancer. Much as early observations of disease associations with HLA polymorphism preceded a detailed knowledge of HLA recognition by T cell receptors, the recently reported disease associations with HLA-KIR gene combinations beg...

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Share to Genes, MHC Class I
Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Peptides

Share to Polymorphism, Genetic

Share to Receptors, Immunologic

Share to Receptors, KIR

Source

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Identifiers

PMID: 15809348
DOI: 10.1084/jem.20050499
PMCID: PMC2213130

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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