Familial Aggregation of Both Aortic and Cerebral Aneurysms: Evidence for a Common Genetic Basis in a Subset of Families

Abstract excerpt

OBJECTIVE: Although previous reports have described patients with both cerebral and aortic aneurysms, any association was believed to be coincidental. In this study, we provide evidence that aortic and cerebral aneurysm formation may share a common genetic predisposition in some families. METHODS: A prospective enrollment of consecutive patients treated for saccular cerebral aneurysm by a single surgeon was...

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