Article
Screening of molecular repertoires by microbial surface display.
Combinatorial chemistry & high throughput screening - 1 Mar 2005
Jostock Thomas, Dübel Stefan
Abstract excerpt
A multitude of systems for the presentation of foreign peptides or proteins on the surface of microorganisms has been developed within the past two decades. However, the majority of the bacterial surface display systems are devoted to the presentation of heterologous antigens to the immune system (vaccine generation). Bacteria are the preferable hosts for the generation of vast genetic repertoires, and their...
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