Article
Identification of mutants in inbred Xenopus tropicalis.
Mechanisms of development - 1 Mar 2005
Grammer Timothy C, Khokha Mustafa K, Lane Maura A, Lam Kentson, Harland Richard M
Abstract excerpt
Xenopus tropicalis offers the potential for genetic analysis in an amphibian. In order to take advantage of this potential, we have been inbreeding strains of frogs for future mutagenesis. While inbreeding a population of Nigerian frogs, we identified three mutations in the genetic background of this strain. These mutations are all recessive embryonic lethals. We show that multigenerational mutant analysis is...
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