Article
High density lipoprotein deficiency syndrome in chickens is not associated with an increased susceptibility to atherosclerosis.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 May 1992
Poernama F, Subramanian R, Cook M E, Attie A D
Abstract excerpt
A spontaneous high density lipoprotein (HDL) deficiency syndrome in chickens associated with a Z-linked (sex-linked) mutation has been reported (F. Poernama et al, J Lipid Res 1990;31:955-963). The mutant, called WHAM (Wisconsin hypo-alpha mutant), has a 70-90% reduction in plasma HDL cholesterol and apolipoprotein A-I (apo A-I) concentrations. In the present study, the effect of the HDL deficiency on...
Topics
- Animals
- Apolipoprotein A-I
- Arteriosclerosis
- Chickens
- Cholesterol
- Diet
- Disease Susceptibility
- Lipoproteins
- Lipoproteins, HDL
- Mutation
- Osmolar Concentration