Asians with cystic fibrosis in the UK have worse disease outcomes than clinic matched white homozygous delta F508 controls.

Abstract excerpt

BACKGROUND: We tested the hypothesis that the Asian cystic fibrosis (CF) phenotype is comparable to the commonest genetic form of CF found in 50% of the white UK CF population using the UK CF Database, a national disease-specific patient registry. METHODS: 50 Asian CF patients were matched by Centre with 143 white homozygous delta F508 patients for gender, age and chronic Pseudomonas aeruginosa status (a marker...

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