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Article

CFTR genotype analysis of Asians in international registries highlights disparities in the diagnosis and treatment of Asian patients with cystic fibrosis.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Oct 2022

Vaidyanathan Sriram, Trumbull Annie M, Bar Lilly, Rao Manaeha, Yu Yunnan, Sellers Zachary M

Abstract excerpt

PURPOSE: Cystic fibrosis (CF) is not well-characterized in Asians, potentially resulting in delayed diagnosis and poor prognosis. We characterized CF in Asian subgroups to address these disparities. METHODS: De-identified ethnicity and CFTR variant data were obtained from the United States, United Kingdom, and Canadian CF registries. We measured the prevalence of CF, CFTR variant allele frequencies, effectiveness...

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PMID: 35857025
DOI: 10.1016/j.gim.2022.06.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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