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Article

AML M3 and AML M3 variant each have a distinct gene expression signature but also share patterns different from other genetically defined AML subtypes.

Genes, chromosomes & cancer - 1 Jun 2005

Haferlach Torsten, Kohlmann Alexander, Schnittger Susanne, Dugas Martin, Hiddemann Wolfgang, Kern Wolfgang, Schoch Claudia

Abstract excerpt

Acute promyelocytic leukemia (APL) with t(15;17) appears in two phenotypes: AML M3, with abnormal promyelocytes showing heavy granulation and bundles of Auer rods, and AML M3 variant (M3v), with non- or hypogranular cytoplasm and a bilobed nucleus. We investigated the global gene expression profiles of 35 APL patients (19 AML M3, 16 AML M3v) by using high-density DNA-oligonucleotide microarrays. First, an...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Gene Expression Profiling

Share to Leukemia, Promyelocytic, Acute

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Source

Identifiers

PMID: 15751046
DOI: 10.1002/gcc.20175

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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