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Potential Limitations of the 16S-23S rRNA Intergenic Region for Molecular Detection of Bartonella Species

1 Mar 2005

Abstract excerpt

PCR targeting the 16S-23S rRNA gene intergenic transcribed spacer (ITS) region has been proposed as a rapid and reliable method for the detection of Bartonella species DNA in clinical samples. Because of variation in ITS sequences among Bartonella species, a single PCR amplification can be used to detect different species within this genus. Therefore, by targeting the ITS region, multiple PCRs or additional...

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PMID: 15750079
DOI: 10.1128/jcm.43.3.1171-1176.2005

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