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Article

Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.

American journal of respiratory and critical care medicine - 15 Jun 2005

Fliegauf Manfred, Olbrich Heike, Horvath Judit, Wildhaber Johannes H, Zariwala Maimoona A, Kennedy Marcus, Knowles Michael R, Omran Heymut

Abstract excerpt

RATIONALE: Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder characterized by recurrent infections of the airways and situs inversus in half of the affected offspring. The most frequent genetic defects comprise recessive mutations of DNAH5 and DNAI1, which encode outer dynein arm (ODA) components. Diagnosis of PCD usually relies on electron microscopy, which is technically demanding and...

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Source

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Identifiers

PMID: 15750039
DOI: 10.1164/rccm.200411-1583OC
PMCID: PMC2718478

Genes

DNAH5
DNAH9
DNAI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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