Article
Isolation of virus from a SARS patient and genome-wide analysis of genetic mutations related to pathogenesis and epidemiology from 47 SARS-CoV isolates.
Virus genes - 1 Jan 2005
Zhu Ying, Liu Mo, Zhao Weiguang, Zhang Jianlin, Zhang Xue, Wang Ke, Gu Chunfang, Wu Kailang, Li Yan, Zheng Congyi, Xiao Gengfu, Yan Huimin, Zhang Jiamin, Guo Deyin, Tien Po, Wu Jianguo
Abstract excerpt
Severe acute respiratory syndrome (SARS) caused by SARS-associated coronavirus (SARS-CoV) is a fatal disease. Prevention of future outbreaks is essential and requires understanding pathogenesis and evolution of the virus. We have isolated a SARS-CoV in China and analyzed 47 SARS-CoV genomes with the aims to reveal the evolution trends of the virus and provide insights into understanding pathogenesis and SARS...
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