Article
Comparative full-length genome sequence analysis of 14 SARS coronavirus isolates and common mutations associated with putative origins of infection.
Lancet (London, England) - 24 May 2003
Ruan Yi Jun, Wei Chia Lin, Ee Ai Ling, Vega Vinsensius B, Thoreau Herve, Su Se Thoe Yun, Chia Jer-Ming, Ng Patrick, Chiu Kuo Ping, Lim Landri, Zhang Tao, Peng Chan Kwai, Lin Ean Oon Lynette, Lee Ng Mah, Yee Sin Leo, Ng Lisa F P, Chee Ren Ee, Stanton Lawrence W, Long Philip M, Liu Edison T
Abstract excerpt
BACKGROUND: The cause of severe acute respiratory syndrome (SARS) has been identified as a new coronavirus. Whole genome sequence analysis of various isolates might provide an indication of potential strain differences of this new virus. Moreover, mutation analysis will help to develop effective vaccines. METHODS: We sequenced the entire SARS viral genome of cultured isolates from the index case (SIN2500)...
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