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Founders’ Lecture. Human spermatozoa: fruits of creation, seeds of doubt

21 Sept 2004

Abstract excerpt

Deoxyribonucleic acid damage in the male germline is associated with defective fertilisation, impaired embryonic development, reduced implantation, abortion and childhood disease. Oxidative stress and the retention of excess residual cytoplasm by the spermatozoa are frequently associated with the induction of such damage. The redox cycling of xenobiotics by oxido-reductases in the germline, the patient's age, the...

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PMID: 15740688
DOI: 10.1071/rd04083

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