Article
Genetic susceptibility to prostate, breast, and colorectal cancer among Nordic twins.
Biometrics - 1 Mar 2005
Baker Stuart G, Lichtenstein Paul, Kaprio Jaakko, Holm Niels
Abstract excerpt
To investigate the role of genetics in the development of cancer, we developed a new approach to analyze data on prostate, breast, and colorectal cancer from the Swedish, Danish, and Finnish twin registries on monozygotic (MZ) and same-sex dizygotic (DZ) twins. In the spirit of a sensitivity analysis, we modeled genetic inheritance as either an autosomal recessive or dominant cancer susceptibility (CS) genotype...
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